Seven Awesome Things You Can Learn From Movies On Shrooms

Psilocybin, a psychedelic compound that can be extracted from more than 200 species of mushrooms, can re-establish contact in a rat brain. That is the conclusion of a new study examining structural changes in the brain that may explain the long-term effects of psilocybin for stress management.

10% increase in communication

The study was led by researchers from Yale University. Senior author Alex Kwan, an associate movies on shrooms of psychology and neuroscience, said in a press statement: "We not only saw a 10% increase in neuronal number, but also on average they were 10% larger, so communication was stronger. "

The antidepressant effects of psilocybin and its active ingredient, psilocin, have been widely studied since the compound was named Breakthrough Therapy for treating depression by the US Food and Drug Administration in 2019.

1. This initiated many clinical trials on the
2. Therapeutic effects of the drug
3. But the question of how
4. These potential effects can be
5. Achieved in the brain
6. Remains unanswered

Plastic brain

Kwan and his team want to investigate whether mutations in dendrites, the small brain thegaiavoice.com that help coordinate signals sent to other nerve cells, may be involved. Dendrites are high-density plastic, growing and shrinking due to neurobiological changes.

https://youtu.be/YusJzqw4Gt0

In depression, human studies show that the number of dendritic and size in the prefrontal cortex decreases. Kwan's team wanted to see if psilocybin treatment in mice could affect dendritic congestion.

To find out, Kwan

Team used a powerful two-photon microscopy to scan the synapse congestion in a mouse prefrontal cortex. The researchers were able to photograph brain lengths using this procedure, which means they could test how dendritic formation changed in the first 24 hours after The Gaia Voice treatment, and then repeat for the first week after dosing.

This was the key to determining the strength and endurance of the dendritic network formed. Researchers have shown that about 50 percent of the connections made immediately after a draw remain the same after a week.

• A final analysis
• 34 days later showed that
• About a third of
• The contacts
• Had not changed

These findings are key to mocking one of the central mysteries of psilocybin research - why a combination that mushroom short-term behavioral changes should produce a long-lasting stress relief effect.

Serotonin signaling

To test this variance further, the team treated the mice with a compound called ketanserin, which inhibits the signaling of serotonin 5-HT2A receptors, which are thought to be responsible for the brain journey obtained when taking magic mushrooms.

Mice may not tell us that they experience a deep psychedelic experience, but they show direct headaches movies on shrooms after taking psilocybin, which is used as an indicator of serotonin receptor stimulation.

The researchers noted that while ketanserin suppressed these behaviors, they did not contribute to dendritic changes. This may suggest, say researchers, that psychedelic and antidepressant effects of psilocybin may be divided.