An Expert Interview About Good Movies to Watch On Shrooms
Indirect evidence of the role of 5-HT2A receptors in combating psychedelic deception comes from a study conducted by Huot et al. (2010). In that study, [3H] ketanserin binding was used to compare 5-HT2A receptor congestion in mushroom brain patients with Parkinson's disease (PD) who experienced visual acuity and brain in PD patients who did not see abnormalities.
Six brains from idiopathic
PD patients who saw no visual cues were compared with six PD patients without visual cues and five healthy, age-related controls. In PD patients with a different vision, ketanserin [3H] binding increased by 45.6% in the temporal inferolateral cortex compared with PD good movies to watch on shrooms who did not have visual acuity.
The authors suggest that increased 5-HT2A concentration in the temporal inferolateral cortex may be the basis for visual perception in PD patients and that 5HT2A antagonists may reduce this symptom.
Similarly, Ballanger et al
(2010) measured 5-HT2A binding in vivo using [18F] setoperone PET in the brains of seven PD patients with thegaiavoice.com acuity and PD patients equal to seven years without visual acuity.
- Patients with different visual acuity have
- Significantly increased 5-HT2A receptor
- Binding in several cortical regions
- And one subcortical region
- These elevated levels of 5-HT2A receptor
- Expression have been implicated mainly
- In the ventral view pathway
With evidence of increased
5-HT2A receptor expression as a possible basis for visual cues in PD patients, the serotonin 5-HT2A inverse agonist, perhaps not surprising, has shown clinical efficacy for phase 3 in the treatment of several symptoms of PD psychosis, The Gaia Voice visual acuity (Hacksell et al., 2014).
Halberstadt et al. (2011a) examined the effects of several psychedelics on the response of mouse head twitch (HTR) to wild type (WT) male C57BL / 6J or 5-HT2A knockout (KO) mice.
They also evaluated the function
Of the probe and the loomotor in the mouse behavior pattern (BPM) monitor. Psilocin and 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) produced HTR in WT mice but not in KO mice.
Psilocin and 5-MeO-DMT reduced locomotor activity, investigative behavior, and intermediate duration in BPM, and these effects were blocked by selective 5-HT1A antagonist WAY-100635 (N - [2 - [4 - (2-methoxyphenyl)]) -1-piperazinyl] ethyl] - N- (2-pyridyl) cyclohexanecarboxamide), good movies to watch on shrooms that psilocin and 5-MeO-DMT act as 5-HT1A / 5- agonists HT2A is mixed.
Halberstadt and Geyer (2011) reviewed several literature on the association of various indoleamines with LSD and concluded that although phenethylamines primarily exert their effects on 5-HT2A receptors, indoleamines may play an important role in linked behaviors. by the activation of 5-HT1A. .
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